Pharmacology Scientist – I (Assistant)

Integrated Resources, Inc
Published
September 10, 2021
Location
West Point, PA
Category
Job Type

Description

Job Title: Pharmacology Scientist - I (Assistant)

Location: West Point, PA

Duration: 12+ months

Job Description:

  • Translational Imaging is responsible for discovery, development, qualification and deployment Client in vivo imaging biomarkers to impact pipeline decisions in preclinical discovery through clinical proof-of-concept at Client Research Laboratories.
  • TIB is looking for a scientist with experience in pharmacology and biochemistry research experience including ligand binding assay in support of the discovery and qualification of Client alpha-synuclein imaging agents for treatment in patients with Parkinson’s disease.
  • The individual will have the following responsibilities: Develop and perform in vitro radioligand binding assays, including autoradiography and tissue homogenate binding assays in human, non-human primate, and rodent brain tissues to assess the binding characteristics of candidate alpha-synuclein radioligands.
  • Prepare samples and, reagents, maintain equipment, track of laboratory consumables.
  • Utilize molecular pharmacology and imaging techniques to assess in vitro, ex vivo, distribution, and specificity of lead compounds and imaging candidates.
  • Analyze results from radioligand binding assays using MCID and/or Prism software.
  • Enter experiments to electric notebooks and present experimental results at group meetings and project meetings.

Qualifications:

  • Education Minimum Requirement: BS in Pharmacology or a related discipline (Biochemistry, Biology etc.) Required Experience and Skills: A minimum of 4 years of direct experience in the development and execution of in vitro pharmacology assays.
  • Strong interpersonal, verbal and written communication skills.
  • Be able to work independently, strong leadership skills.
  • Ability to execute within a matrixed organization Preferred Experience and Skills.
  • Experience performing ligand binding assays.
  • Experience handling radioactivity.
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